BIPN 145 Neurobiology Laboratory (WI27)#
Welcome to BIPN 145! This is a course about how we study the nervous system. You’ll be asked to think, plan, and write like a neuroscientist.
You may be surprised about some of the topics in this course. You’ll spend a lot of time learning about nervous systems, but we’ll also spend some time talking about experimental design, technology, ethics, and analyzing big data sets.
Course details#
Instructional Team#
Role |
Name |
|
|---|---|---|
Instructor |
Ashley Juavinett |
|
Teaching Assistant |
TBD |
TBD |
Reader |
TBD |
— |
Peer Learning Assistant (PLA) |
TBD |
— |
Staff Research Associate |
Breonna Gonzalez |
— |
Office hours: By appointment
Lecture: MWF 11:00–11:50 am in COA 117
Lab: Friday 12:30-4:20 pm in York Hall 1310
Course learning objectives#
Collect and evaluate neural data from various organisms
Apply principles of neural communication to multiple model systems
Describe the breadth of techniques in neuroscience and the experimental questions they are suited to answer
Develop an appreciation for and practical insight into the process of research
Communicate research to peers as well as a broader audience
Attendance policies#
You are expected to attend our in-person lab sessions, and some lectures are mandatory. All lecture sessions will be podcasted/recorded, but you will be expected to make up any in-class activities that you missed.
If you cannot attend a lab session due to illness or for any other reason, please contact both Dr. J and our teaching assistant(s) ASAP so that we can work with you on accommodations.
Enrolled and waitlisted students must attend the first lab session. Additional details: http://biology.ucsd.edu/go/ug-labs. You do not need to inform us if you will be missing a lecture session.
Grading#
QUIZZES & ASSIGNMENTS (350 pts, 20–50 pts each) — Includes quizzes for individual lab activities and pre-lab quizzes.
EARTHWORM REPORT (125 pts) — Your first lab report will summarize our earthworm experiments.
FINAL PROJECT (250 pts) — Project proposal, presentation, and written report.
MIDTERMS (250 pts, 125 pts each)
PROFESSIONALISM (25 pts)
Late assignments#
For individual assignments only, you have a 3-day late bank that you may use over the course of the session to extend your deadlines without penalty.
You can request a late bank before the deadline by filling out this form: https://forms.gle/SAeRJKyCWRtdhbFx7.
Assignments not protected by the late bank will lose -10% for each day they are late.
In the case of extenuating circumstances requiring a submission more than three days late, please contact Dr. J directly.
Additional notes on grading#
Final scores will be converted to letter grades, where A = 90–100%, B = 80–89.99%, C = 70–79.99%, D = 60–69.99%, and F = 0–59.99%. For plus and minus grades, A+ = 97–100, A = 93–96.99, A- = 90–92.99, B+ = 87–89.99, B = 83–86.99, B- = 80–82.99, and so on.
Final scores are as you see them on Canvas, once all of your assignments are graded. There is no rounding up to the closest score.
Please note that add/drop deadlines are different for lab courses than lecture courses. Students who drop a Biology lab class after the end of the second class meeting will be assigned a “W”. Additional details: http://biology.ucsd.edu/go/ug-labs.
Course philosophy#
A note on our course’s environment#
We’ll be working together to create an equitable and inclusive environment of mutual respect, in which we all feel comfortable to share our moments of confusion, ask questions, and challenge our understanding. Everyone should be able to succeed in this course. If you do not feel that is the case please let me know.
To help accomplish this:
I’ll ask for your preferred name & pronouns on our incoming survey. If these change over the course of the session, please let me know.
Please don’t hesitate to come and talk with me if you feel like your performance in the class is being impacted by your experiences outside of class.
I am constantly learning about diverse perspectives and identities. If something was said in class (by anyone) that made you feel uncomfortable, please talk to me about it.
As a participant, you should also strive to honor the diversity of your classmates.
Course accommodations#
If you need accommodations for this course due to a disability, please contact the Office for Students with Disabilities (osd@ucsd.edu) for an Authorization for Accommodation letter. Please speak with me in the first week of class if you intend to apply for accommodations. For more information, visit http://disabilities.ucsd.edu.
This course, and the work it entails, is for you#
So, you won’t benefit if others (or a generative AI) do your work. Cases of academic dishonesty or cheating will be first handled by me, and then by the Academic Integrity Office. If you become aware of cheating in this class, you can anonymously report it: https://academicintegrity.ucsd.edu/
Lab safety is important#
Enrolled and waitlisted students must successfully complete the Biology Lab Safety Training and Assessment before the first lab session: https://biolabclass-safetyquiz.ucsd.edu/introduction. You will not be allowed into the lab for the second in-person lab session unless you have successfully passed the safety assessment. Note that you do not need to bring your own personal protective equipment (e.g. a lab coat or goggles) for this course. We will provide gloves when needed.
Course management & texts#
Lab Manual: The lab manual is contained on the same website as this syllabus, which also contains lots of links to supplementary materials.
Canvas: This course will be using Canvas to manage content and grades. You can log in by going to http://canvas.ucsd.edu. If you need any technical assistance with Canvas, please alert your instructor and send an email to servicedesk@ucsd.edu.
Textbook: There is no mandated textbook for this course, but most of the background material can be found in Purves et al. (2018) Neuroscience. We’ll also use Carter & Shieh (2015) Guide to Research Techniques in Neuroscience.
Software for this class#
It will be helpful to have the following software on your personal computer. If you have any issues with these or would prefer not to download anything onto your personal computer, you are welcome to rely on a teammate or reach out to us for additional accommodations. If you need a laptop, you can request one.
Microsoft Office: It may be useful to have Microsoft Office in this course. You can find it here.
LabChart Reader: Please download LabChart Reader on your personal computer. We’ll be using this to analyze data you collect.
Course schedule#
Schedule subject to change
Please note this is tentative. Please rely on Canvas for assignment due dates.
Date |
Topic |
Due/Reading |
|
|---|---|---|---|
Week 1 |
|||
Jan 4 |
Lecture |
An introduction to BIPN 145 & nervous systems |
Take the incoming survey (link on Canvas) |
Jan 6 |
Lecture |
Modeling neural activity |
|
Jan 8 |
Lecture |
Neuromembrane activity (MANDATORY) |
|
Lab |
Group formation & scavenger hunt |
Take the online safety test. |
|
Week 2 |
|||
Jan 11 |
Lecture |
Recording from the nervous system |
|
Jan 13 |
Lecture |
The action potential |
READ Hodgkin & Huxley (1939) |
Jan 15 |
Lecture |
Earthworm nervous systems |
DUE Neuromembrane Quiz & Earthworm Pre-Lab Quiz |
Lab |
String Lab & RC Circuits |
WATCH/READ Exporting data from LabChart |
|
Week 3 |
|||
Jan 18 |
No lecture |
Martin Luther King, Jr. Day |
|
Jan 20 |
Lecture |
Writing lab reports |
DUE String Lab & RC Circuit Quiz |
Jan 22 |
Lecture |
The speed of the nervous system |
|
Lab |
Earthworm Experiments |
||
Week 4 |
|||
Jan 25 |
Lecture |
Earthworm Data Analysis (MANDATORY) |
|
Jan 27 |
Lecture |
Intracellular & patch clamp recording |
|
Jan 29 (drop deadline) |
Lecture |
Leech Physiology & Cell Types |
DUE Leech Pre-Lab Quiz |
Lab |
Intracellular Equipment |
||
Week 5 |
|||
Feb 1 |
Lecture |
Leech Paper Discussion (MANDATORY) |
DUE Earthworm Lab Report |
Feb 3 |
Lecture |
How is science funded? & Introduction to final projects |
|
Feb 5 |
Lecture |
Review for the exam |
|
Lab |
Leech Experiments |
||
Week 6 |
|||
Feb 8 |
Lecture |
Exam #1 |
|
Feb 10 |
Lecture |
Ethology & behavior |
|
Feb 12 (deadline to drop w/ “W”) |
Lecture |
Drosophila Behavior (MANDATORY) |
READ your Drosophila behavior handout |
Lab |
Leech Experiments (Continued) |
||
Week 7 |
|||
Feb 15 |
No lecture |
Presidents’ Day |
Submit Final Project Equipment & Needs [Spreadsheet] |
Feb 17 |
Lecture |
Leech Data Analysis (MANDATORY) |
DUE Sunday, Feb 14 @ 11:59 pm: Project proposals |
Feb 19 |
Lecture |
Drosophila Optogenetics |
|
Lab |
|||
Week 8 |
|||
Feb 22 |
Lecture |
Electroencephalography (EEG) |
|
Feb 24 |
Lecture |
Mapping neural circuits & 21st century neuroscience techniques |
|
Feb 26 |
Lecture |
Drosophila Presentations |
DUE Thursday @ 11:59 pm: Drosophila Presentation slides |
Lab |
|||
Week 9 |
|||
Mar 1 |
Lecture |
EEG Data Analysis (MANDATORY) |
|
Mar 3 |
Lecture |
Final project planning |
DUE EEG Quiz & Results |
Mar 5 |
Lecture |
Allen Institute data activity (MANDATORY) |
|
Lab |
Work on final projects |
||
Week 10 |
|||
Mar 8 |
Lecture |
Review for Exam #2 |
|
Mar 10 |
Lecture |
Exam #2 |
|
Mar 12 |
Lecture |
Careers in neuroscience |
|
Lab |
Work on final projects |
||
TBD |
Final exam period (Mar 13–20) |
Final Projects Symposium (date & time TBD) |